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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Olsalazine

Dipentum 250 mg capsule

$1.8

capsule

* price without discount in nearest pharmacy. Price may vary.

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Olsalazine volume of distribution

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What is Olsalazine

Olsalazine is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease and Ulcerative Colitis. Olsalazine is a derivative of salicylic acid. Inactive by itself (it is a prodrug), it is converted by the bacteria in the colon to mesalamine. Mesalamine works as an anti-inflammatory agent in treating inflammatory diseases of the intestines.

Olsalazine mechanism of action

Orally administered olsalazine is converted to mesalamine which is thought to be the therapeutically active agent in the treatment of ulcerative colitis. The mechanism of action of mesalamine (and sulfasalazine) is unknown, but appears to be topical rather than systemic. Mucosal production of arachidonic acid (AA) metabolites, both through the cyclooxygenase pathways, i.e., prostanoids, and through the lipoxygenase pathways, i.e., leukotrienes (LTs) and hydroxyelcosatetraenoic acids (HETEs) is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalamine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin (PG) production in the colon.

Dosage forms of Olsalazine

DrugDosageQuantityPrice
Dipentum250mg100 Capsule$99.00
Prescription Generics

false

International Brands

Dipentum

Synonyms

Dipentum

Manufacturers

Alaven Pharmaceutical LLC

CAS number

15722-48-2

UNII

ULS5I8J03O

State

solid

Affected organisms

Humans and other mammals

Indication of Olsalazine

For the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.

Toxicity of Olsalazine

Maximum single oral doses of 5g/kg in mice and rats and 2 g/kg in dogs were not lethal.

RX24 Drugs Disclaimer: before buying a Olsalazine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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