Save up -80% on Olsalazine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Dipentum
|price without discount in nearest pharmacy. Price may vary.|
We offer free Olsalazine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Olsalazine every time. What are you waiting for? Claim your prescription drug card now!
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Olsalazine volume of distribution
A low volume of distribution, mean 5.71.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Olsalazine
Olsalazine is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease and Ulcerative Colitis. Olsalazine is a derivative of salicylic acid. Inactive by itself (it is a prodrug), it is converted by the bacteria in the colon to mesalamine. Mesalamine works as an anti-inflammatory agent in treating inflammatory diseases of the intestines.
Olsalazine mechanism of action
Orally administered olsalazine is converted to mesalamine which is thought to be the therapeutically active agent in the treatment of ulcerative colitis. The mechanism of action of mesalamine (and sulfasalazine) is unknown, but appears to be topical rather than systemic. Mucosal production of arachidonic acid (AA) metabolites, both through the cyclooxygenase pathways, i.e., prostanoids, and through the lipoxygenase pathways, i.e., leukotrienes (LTs) and hydroxyelcosatetraenoic acids (HETEs) is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalamine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin (PG) production in the colon.
Dosage forms of Olsalazine
Alaven Pharmaceutical LLC
Humans and other mammals
Indication of Olsalazine
For the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.
Toxicity of Olsalazine
Maximum single oral doses of 5g/kg in mice and rats and 2 g/kg in dogs were not lethal.
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