Save up -80% on Ondansetron
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Zofran
|$7.53||10 orally disintegrating tabs/4 mg|
|price without discount in nearest pharmacy. Price may vary.|
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Ondansetron volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Ondansetron
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Ondansetron mechanism of action
Ondansetron is a selective serotonin 5-HTsub3/sub receptor antagonist. The antiemetic activity of the drug is brought about through the inhibition of 5-HTsub3/sub receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HTsub3/sub receptors in turn inhibits the visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone.
Dosage forms of Ondansetron
|Injection||intramuscular; intravenous||2 mg/mL|
|Injection, solution||intramuscular||2 mg/mL|
|Injection, solution||intramuscular; intravenous||4 mg/2mL|
Actavis Pharma Company
Humans and other mammals
Indication of Ondansetron
For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment of postoperative nausea and vomiting.
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