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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ondansetron

Apo-Ondansetron 0.8 mg/ml Solution

$1.53

ml

* price without discount in nearest pharmacy. Price may vary.

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Ondansetron volume of distribution

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What is Ondansetron

A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Ondansetron mechanism of action

Ondansetron is a selective serotonin 5-HTsub3/sub receptor antagonist. The antiemetic activity of the drug is brought about through the inhibition of 5-HTsub3/sub receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HTsub3/sub receptors in turn inhibits the visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone.

Dosage forms of Ondansetron

FormRouteStrength
Injectionintramuscular; intravenous2 mg/mL
Injection, solutionintramuscular2 mg/mL
Injection, solutionintramuscular; intravenous4 mg/2mL
Prescription Generics

false

International Brands

Act Ondansetron

Synonyms

Zofran odt

Manufacturers

Actavis Pharma Company

CAS number

99614-02-5

UNII

4AF302ESOS

State

solid

Affected organisms

Humans and other mammals

Indication of Ondansetron

For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment of postoperative nausea and vomiting.

Toxicity of Ondansetron

Low blood pressure and fainting, sudden blindness, severe constipation

RX24 Drugs Disclaimer: before buying a Ondansetron on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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