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Price of Orciprenaline
Metaproterenol 10 mg tablet
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Orciprenaline volume of distribution
What is Orciprenaline
A beta-adrenergic agonist used in the treatment of asthma and bronchospasms. (PubChem)
Orciprenaline mechanism of action
Orciprenaline is a moderately selective beta(2)-adrenergic agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature supplying skeletal muscle, with minimal or no effect on alpha-adrenergic receptors. Intracellularly, the actions of orciprenaline are mediated by cAMP, the production of which is augmented by beta stimulation. The drug is believed to work by activating adenylate cyclase, the enzyme responsible for producing the cellular mediator cAMP.
Dosage forms of Orciprenaline
|Aerosol||inhalation; oral||.75 mg|
|Liquid||inhalation; oral||50 mg|
Boehringer Ingelheim (Canada) Ltd Ltee
Humans and other mammals
Indication of Orciprenaline
For the treatment of bronchospasm, chronic bronchitis, asthma, and emphysema.
Toxicity of Orciprenaline
Symptoms of overdose include angina, hypertension or hypotension, arrhythmias, nervousness, headache, tremor, dry mouth, palpitation, nausea, dizziness, fatigue, malaise and insomnia. LDsub50/sub=42 mg/kg (orally in rat).
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