Save up -80% on Orlistat
Note: this is a drug discount program, not an insurance plan.
2018 Price of Orlistat
Xenical 120 mg capsule
* price without discount in nearest pharmacy. Price may vary.
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Orlistat volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Orlistat
Orlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. Orlistat works by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.
Orlistat mechanism of action
Orlistat is a reversible inhibitor of lipases. It exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine residue site of gastric and pancreatic lipases. The inactivated enzymes are thus unavailable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglycerides. As undigested triglycerides are not absorbed, the resulting caloric deficit may have a positive effect on weight control.
Dosage forms of Orlistat
|Capsule, hard||Oral use||60 mg|
|Chewable tablet||Oral use||27 mg|
Glaxo Smith Kline Consumer Healthcare Holdings (Us) Llc
Humans and other mammals
Indication of Orlistat
For obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Also used to reduce the risk for weight regain after prior weight loss. Use of orlistat is pending revision due to reports of liver-related adverse events.
Toxicity of Orlistat
The results of a massive overdose of Xenical are unknown, although the drug seems relatively harmless.
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