Save up -80% on Orphenadrine
Note: this is a drug discount program, not an insurance plan.
2018 Price of Orphenadrine
Orphenadrine comp tablet
* price without discount in nearest pharmacy. Price may vary.
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Orphenadrine volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Orphenadrine mechanism of action
Orphenadrine binds and inhibits both histamine H1 receptors and NMDA receptors. It restores the motor disturbances induced by neuroleptics, in particular the hyperkinesia. The dopamine deficiency in the striatum increases the stimulating effects of the cholinergic system. This stimulation is counteracted by the anticholinergic effect of orphenadrine. It may have a relaxing effect on skeletal muscle spasms and it has a mood elevating effect.
Dosage forms of Orphenadrine
|Liquid||intramuscular; intravenous||30 mg|
Disipal Tab 50mg
3 M Pharmaceuticals, A Division Of 3 M Canada Company
Humans and other mammals
Toxicity of Orphenadrine
Oral, mouse LD sub50 /sub = 100 mg/kg; oral, rat LD sub50 /sub = 255 mg/kg
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