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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Oxcarbazepine

Oxcarbazepine 150 mg tablet



* price without discount in nearest pharmacy. Price may vary.

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Oxcarbazepine volume of distribution

* 49 L

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What is Oxcarbazepine

Oxcarbazepine is structurally a derivative of carbamazepine, adding an extra oxygen atom to the benzylcarboxamide group. This difference helps reduce the impact on the liver of metabolizing the drug, and also prevents the serious forms of anemia occasionally associated with carbamazepine. Aside from this reduction in side effects, it is thought to have the same mechanism as carbamazepine – sodium channel inhibition – and is generally used to treat partial seizures in epileptic children and adults.

Oxcarbazepine mechanism of action

The exact mechanism by which oxcarbazepine exerts its anticonvulsant effect is unknown. It is known that the pharmacological activity of oxcarbazepine occurs primarily through its 10-monohydroxy metabolite (MHD). In vitro studies indicate an MHD-induced blockade of voltage-sensitive sodium channels, resulting in stabilization of hyperexcited neuronal membranes, inhibition of repetitive neuronal discharges, and diminution of propagation of synaptic impulses.

Dosage forms of Oxcarbazepine

Suspensionoral300 mg/5mL
Tabletoral150 mg/1
Tabletoral300 mg/1
Prescription Generics


International Brands



10,11-Dihydro-10-oxo-5H-dibenz(b,F)azepine-5-carboxamide OCBZ


Apotex Inc

CAS number





Affected organisms

Humans and other mammals

Indication of Oxcarbazepine

For use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy and as adjunctive therapy in the treatment of partial seizures in children ages 4-16 with epilepsy.

Toxicity of Oxcarbazepine

Isolated cases of overdose with oxcarbazepine have been reported. The maximum dose taken was approximately 24,000 mg. All patients recovered with symptomatic treatment.

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