Save up -80% on Oxcarbazepine
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2018 Price of Oxcarbazepine
Oxcarbazepine 150 mg tablet
* price without discount in nearest pharmacy. Price may vary.
We offer free Oxcarbazepine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Oxcarbazepine every time. What are you waiting for? Claim your prescription drug card now!
Oxcarbazepine volume of distribution
* 49 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Oxcarbazepine
Oxcarbazepine is structurally a derivative of carbamazepine, adding an extra oxygen atom to the benzylcarboxamide group. This difference helps reduce the impact on the liver of metabolizing the drug, and also prevents the serious forms of anemia occasionally associated with carbamazepine. Aside from this reduction in side effects, it is thought to have the same mechanism as carbamazepine – sodium channel inhibition – and is generally used to treat partial seizures in epileptic children and adults.
Oxcarbazepine mechanism of action
The exact mechanism by which oxcarbazepine exerts its anticonvulsant effect is unknown. It is known that the pharmacological activity of oxcarbazepine occurs primarily through its 10-monohydroxy metabolite (MHD). In vitro studies indicate an MHD-induced blockade of voltage-sensitive sodium channels, resulting in stabilization of hyperexcited neuronal membranes, inhibition of repetitive neuronal discharges, and diminution of propagation of synaptic impulses.
Dosage forms of Oxcarbazepine
Humans and other mammals
Indication of Oxcarbazepine
For use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy and as adjunctive therapy in the treatment of partial seizures in children ages 4-16 with epilepsy.
Toxicity of Oxcarbazepine
Isolated cases of overdose with oxcarbazepine have been reported. The maximum dose taken was approximately 24,000 mg. All patients recovered with symptomatic treatment.
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