Save up -80% on Pantoprazole
Note: this is a drug discount program, not an insurance plan.
2018 Price of Pantoprazole
Apo-Pantoprazole 40 mg Enteric-Coated Tablet
* price without discount in nearest pharmacy. Price may vary.
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Pantoprazole volume of distribution
* 11.0 to 23.6 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Pantoprazole
Pantoprazole is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
Pantoprazole mechanism of action
Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H sup + /sup ,K sup + /sup )- ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect is dose- related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus.
Dosage forms of Pantoprazole
|Pantoprazole||20mg||100 Delayed Release Tablet (Enteric Coated)||$121.00|
|Pantoprazole||40mg||100 Delayed Release Tablet (Enteric Coated)||$85.05|
|Protonix||20mg||90 Delayed Release Tablet (Enteric Coated)||$119.00|
|Protonix||40mg||30 Delayed Release Tablet (Enteric Coated)||$42.00|
Abbott Laboratories, Limited
Humans and other mammals
Indication of Pantoprazole
Short-term (up to 16 weeks) treatment of erosive esophagitis.
Toxicity of Pantoprazole
Single intravenous doses of pantoprazole at 378, 230, and 266 mg/kg (38, 46, and 177 times the recommended human dose based on body surface area) were lethal to mice, rats and dogs, respectively. The symptoms of toxicity included hypoactivity, ataxia, hunched sitting, limb-splay, lateral position, segregation, absence of ear reflex, and tremor. There is limited experience regarding cases of human overdosage, and treatment should be symptomatic and supportive.
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