Save up -80% on Paricalcitol

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Zemplar

$162.9612 capsules/1mcg
price without discount in nearest pharmacy. Price may vary.

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We offer free Zemplar coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Paricalcitol every time. What are you waiting for? Claim your prescription drug card now!

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Paricalcitol volume of distribution

In healthy subjects, the steady state volume of distribution is approximately 23.8 L. The mean volume of distribution following a 0.24 mcg/kg dose of paricalcitol in CKD Stage 5 subjects requiring hemodialysis (HD) and peritoneal dialysis (PD) is between 31 and 35 L.

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Paricalcitol

Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.

Paricalcitol mechanism of action

Paricalcitol is a synthetic, biologically active vitamin D analog of calcitriol with modifications to the side chain (D2) and the A (19-nor) ring. Preclinical andin vitro studies have demonstrated that paricalcitol’s biological actions are mediated through binding of the VDR, which results in the selective activation of vitamin D responsive pathways. Vitamin D and paricalcitol have been shown to reduce parathyroid hormone levels by inhibiting PTH synthesis and secretion.

Dosage forms of Paricalcitol

DrugDosageQuantityPrice
Zemplar1mcg28 Capsule$195.95
Zemplar1mcg84 Capsule$543.95
Zemplar2mcg28 Capsule$383.95
Zemplar2mcg84 Capsule$1,223.00

Prescription Generics

false

International Brands

Paricalcitol

Synonyms

19-Nor-1alpha,25-dihydroxyvitamin D2 Paricalcitol

Manufacturers

Hospira, Inc.

CAS number

131918-61-1

UNII

6702D36OG5

State

solid

Affected organisms

Humans and other mammals

Indication of Paricalcitol

For treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3 and 4

Toxicity of Paricalcitol

Concurrent administration of thiazide diuretics and pharmacologic doses of vitamin D analogs in patients with hypoparathyroidism may result in hypercalcemia which may be transient and self-limited or may require discontinuance of vitamin D analogs. Thiazide-induced hypercalcemia in hypoparathyroid patients is probably caused by increased release of calcium from bone.

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