Save up -80% on Paricalcitol
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Price of Paricalcitol
Zemplar 1 mcg capsule
* price without discount in nearest pharmacy. Price may vary.
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Paricalcitol volume of distribution
* 30.8 7.5 L (CKD Stage 5-HD)
* 34.9 9.5 L (CKD Stage 5-PD)
* 23.8 L (healthy subjects)
What is Paricalcitol
Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Paricalcitol mechanism of action
Paricalcitol is a synthetic, biologically active vitamin D analog of calcitriol with modifications to the side chain (D2) and the A (19-nor) ring. Preclinical andin vitro studies have demonstrated that paricalcitol’s biological actions are mediated through binding of the VDR, which results in the selective activation of vitamin D responsive pathways. Vitamin D and paricalcitol have been shown to reduce parathyroid hormone levels by inhibiting PTH synthesis and secretion.
Dosage forms of Paricalcitol
Humans and other mammals
Indication of Paricalcitol
For treatment of secondary hyperparathyroidism associated with chronic kidney disease (CKD) Stage 3 and 4
Toxicity of Paricalcitol
Disclaimer: before buying a Paricalcitol on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.