Save up -80% on Pegfilgrastim
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Price of Pegfilgrastim
Neulasta 6 mg/0.6ml Solution 0.6ml Syringe
* price without discount in nearest pharmacy. Price may vary.
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Pegfilgrastim volume of distribution
What is Pegfilgrastim
PEGylated (at N terminus) form of human G-CSF (Granulocyte colony stimulating factor), 175 residues, produced from E. coli via bacterial fermentation.
Pegfilgrastim mechanism of action
Pegfilgrastim binds to the G-CSF receptor. As a G-CSF analog, it controls proliferation of committed progenitor cells and influences their maturation into mature neutrophils. Pegfilgrastim also stimulates the release of neutrophils from bone marrow storage pools and reduces their maturation time. Pegfilgrastim acts to increase the phagocytic activity of mature neutrophils. In patients receiving cytotoxic chemotherapy, pegfilgrastim can accelerate neutrophil recovery, leading to a reduction in duration of the neutropenic phase
Dosage forms of Pegfilgrastim
Granulocyte colony-stimulating factor precursor
Indication of Pegfilgrastim
Increases leukocyte production, for treatment in non-myeloid cancer, neutropenia and bone marrow transplant
Toxicity of Pegfilgrastim
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