Save up -80% on Pegfilgrastim
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Neulasta
|$6,177.14||1 syringe 6mg/0.6ml|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Neulasta coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Pegfilgrastim every time. What are you waiting for? Claim your prescription drug card now!
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Pegfilgrastim volume of distribution
Pegfilgrastim appears to have a volume of distribution of approximately 170L. Pegfilgrastim is thought to be broken down into amino acids similarly to endogenous proteins. Pegfilgrastim clearance by renal filtration is negligible due to the large hydrodynamic radius afforded by the PEG group.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Pegfilgrastim
PEGylated (at N terminus) form of human G-CSF (Granulocyte colony stimulating factor), 175 residues, produced from E. coli via bacterial fermentation.
Pegfilgrastim mechanism of action
Pegfilgrastim binds to the G-CSF receptor. As a G-CSF analog, it controls proliferation of committed progenitor cells and influences their maturation into mature neutrophils. Pegfilgrastim also stimulates the release of neutrophils from bone marrow storage pools and reduces their maturation time. Pegfilgrastim acts to increase the phagocytic activity of mature neutrophils. In patients receiving cytotoxic chemotherapy, pegfilgrastim can accelerate neutrophil recovery, leading to a reduction in duration of the neutropenic phase
Dosage forms of Pegfilgrastim
G-CSF Granulocyte colony-stimulating factor precursor
Indication of Pegfilgrastim
Increases leukocyte production, for treatment in non-myeloid cancer, neutropenia and bone marrow transplant
Toxicity of Pegfilgrastim
The most common adverse events experienced included bone pain and extremity pain. Rarely, leukocytosis was observed after pegfilgrastim administration. As a protein, pegfilgrastim has the potential for immunogenicity but this was observed in less than 1% of studied patients.
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