Save up -80% on Pegvisomant

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Somavert

$181.951 vial/10mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Somavert coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Pegvisomant every time. What are you waiting for? Claim your prescription drug card now!

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Pegvisomant volume of distribution

The mean extent of absorption of a 20-mg subcutaneous dose was 57%, relative to a 10-mg intravenous dose. Distribution The mean apparent volume of distribution of pegvisomant is 7 L (12% coefficient of variation), suggesting that pegvisomant does not distribute extensively into tissues.

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Pegvisomant

Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity.

Pegvisomant mechanism of action

Somavert selectively binds to growth hormone (GH) receptors on cell surfaces, where it blocks the binding of endogenous GH. This leads to the normalization of serum IGF-1 levels.

Dosage forms of Pegvisomant

FormRouteStrength
Kit
Kit; powder for solutionsubcutaneous10 mg
Kit; powder for solutionsubcutaneous15 mg

Prescription Generics

false

International Brands

Somavert

Synonyms

GH GH-N

Manufacturers

Pfizer Canada Inc

CAS number

218620-50-9

UNII

N824AOU5XV

State

liquid

Affected organisms

Humans and other mammals

Indication of Pegvisomant

Pegvisomant is a growth hormone receptor antagonist used for the treatment of acromegaly.

Toxicity of Pegvisomant

PEGv 15 mg every other day was added to lanreotide 120 mg monthly. The patient developed a severe hepatitis five months after starting the combination therapy. Elevated ferritin, iron, and transferrin saturation suggested probable hepatitis due to haemochromatosis. We performed a liver biopsy which showed an acute cholestatic hepatitis consistent with toxic etiology.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Pegvisomant on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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