Save up -80% on Perampanel
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2018 Price of Perampanel
* price without discount in nearest pharmacy. Price may vary.
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Perampanel volume of distribution
The volume of distribution of perampanel was not quantified.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Perampanel
Perampanel is a noncompetitive AMPA glutamate receptor antagonist. It is marketed under the name Fycompa and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. The FDA label includes an important black-boxed warning of serious or life-threatening behavioral and psychiatric reactions in patients taking Fycompa .
Perampanel mechanism of action
The exact mechanism of action of perampanel in seizures is not yet determined, but it is known that perampanel decreases neuronal excitation by non-competitive ihibition of the AMPA receptor.
Dosage forms of Perampanel
|Film-coated tablet||Oral use||10 mg|
|Film-coated tablet||Oral use||12 mg|
|Film-coated tablet||Oral use||2 mg|
Humans and other mammals
Indication of Perampanel
Used in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
Toxicity of Perampanel
The FDA label includes an important warning of serious or life-threatening behavioral and psychiatric adverse reactions including aggression, hostility, irritability, anger, and homicidal thoughts in patients taking perampanel.
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