Save up -80% on Perphenazine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Trilafon
|$13.85||60 tablets/4 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Perphenazine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Perphenazine every time. What are you waiting for? Claim your prescription drug card now!
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Perphenazine volume of distribution
The total body clearance of perphenazine is around 100 L/h with a volume of distribution from 10 to 34 L/kg 7. The half-life of perphenazine is approximately 9.5 hrs with an oral bioavailability of 20%.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Perphenazine
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Perphenazine mechanism of action
Binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. The mechanism of the anti-emetic effect is due predominantly to blockage of the dopamine D2 neurotransmitter receptors in the chemoreceptor trigger zone and vomiting centre. Perphenazine also binds the alpha andrenergic receptor. This receptor’s action is mediated by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Dosage forms of Perphenazine
Apo Peram Tab 2-25
Humans and other mammals
Indication of Perphenazine
For use in the management of the manifestations of psychotic disorders and for the control of severe nausea and vomiting in adults.
Toxicity of Perphenazine
Symptoms of overdose include stupor or coma, and children may have convulsive seizures. Signs of arousal may not occur for 48 hours. Oral LDsub50/sub=318 mg/kg (rat); IPR LDsub50/sub=64 mg/kg (mouse)
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