Save up -80% on Phenobarbital
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Luminal
|$16.63||60 tablets/60 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Phenobarbital coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Phenobarbital every time. What are you waiting for? Claim your prescription drug card now!
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Phenobarbital volume of distribution
The plasma volume of distribution of phenobarbital approximates 0.6–1.0 L/kg, depending on the age of the patient. Children and adults have a smaller volume of distribution (~0.7 L/kg) compared to neonates (~0.9 L/kg).
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Phenobarbital
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Phenobarbital mechanism of action
Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. This has the effect of elevating seizure threshold and reducing the spread of seizure activity from a seizure focus. Phenobarbital may also inhibit calcium channels, resulting in a decrease in excitatory transmitter release. The sedative-hypnotic effects of phenobarbital are likely the result of its effect on the polysynaptic midbrain reticular formation, which controls CNS arousal.
Dosage forms of Phenobarbital
Winder Laboratories, LLC
Humans and other mammals
Indication of Phenobarbital
For the treatment of all types of seizures except absence seizures.
Toxicity of Phenobarbital
CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.
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