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Price of Phentermine
Phentermine HCl 37.5 mg capsule
* price without discount in nearest pharmacy. Price may vary.
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Phentermine volume of distribution
What is Phentermine
A central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. It has been used most frequently in the treatment of obesity. (PubChem). Some common brand names for phentermine are Adipex-P and Suprenza. Phentermine is also available in combination medications such as Qsymia.
Phentermine mechanism of action
Phentermine is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these include dopamine and norepinephrine. High levels of these catecholamines tend to suppress hunger signals and appetite. The drug seems to inhibit reuptake of noradrenaline, dopamine, and seratonin through inhibition or reversal of the reuptake transporters. It may also inhibit MAO enzymes leaving more neurotransmitter available at the synapse.Phentermine (through catecholamine elevation) may also indirectly affect leptin levels in the brain. It is theorized that phentermine can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger known as neuropeptide Y. This peptide initiates eating, decreases energy expenditure, and increases fat storage.
Dosage forms of Phentermine
A S Medication Solutions Llc
Humans and other mammals
Indication of Phentermine
For the treatment and management of obesity.
Toxicity of Phentermine
LD sub 50 /sub is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
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