Save up -80% on Pilocarpine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Salagen
|price without discount in nearest pharmacy. Price may vary.|
We offer free Salagen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Pilocarpine every time. What are you waiting for? Claim your prescription drug card now!
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Pilocarpine volume of distribution
At doses between 0.5 and 3.5 mg, dose-independent pharmacokinetic parameters included a small steady-state volume of distribution (2.4 to 3.0 L/kg), a high plasma clearance (0.026 to 0.03 L/kg/min), and a mean residence time of approximately 100 min.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Pilocarpine
A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
Pilocarpine mechanism of action
Pilocarpine is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary muscle (when given topically to the eyes) by mainly stimulating muscarinic receptors.
Dosage forms of Pilocarpine
|Isopto Carpine||2%||15mL Eyedrops||$36.00|
|Isopto Carpine||4%||15mL Eyedrops||$36.50|
Alcon Canada Inc
Humans and other mammals
Indication of Pilocarpine
For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjouml;grens syndrome.
Toxicity of Pilocarpine
Pilocarpine has been used as an ophthalmologic agent for decades; however, toxicity rarely has been reported in the medical literature. Oral pilocarpine tablets, as well as another muscarinic agent (cevimeline), have recently been approved for the treatment of dry mouth (xerostomia). We report a case of unintentional overdose of oral pilocarpine tablets that resulted in bradycardia, mild hypotension, and muscarinic symptoms in a patient with Sjogren’s syndrome. The patient’s symptoms were relieved with 0.5 mg intravenous atropine and she recovered uneventfully.
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