Save up -80% on Pimecrolimus

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Pimecrolimus

Elidel 1% cream

$3.21

g

* price without discount in nearest pharmacy. Price may vary.

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Pimecrolimus volume of distribution

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What is Pimecrolimus

Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis (eczema). It is currently available as a topical cream, once marketed by Novartis, (however Galderma will be promoting the molecule in Canada in early 2007) under the trade name Elidel. (Wikipedia)

Pimecrolimus mechanism of action

Pimecrolimus binds with high affinity to macrophilin-12 (FKBP-12) and inhibits the calcium-dependent phosphatase, calcineurin. As a consequence, it inhibits T cell activation by blocking the transcription of early cytokines. In particular, pimecrolimus inhibits at nanomolar concentrations Interleukin-2 and interferon gamma (Th1-type) and Interleukin-4 and Interleukin-10 (Th2-type) cytokine synthesis in human T cells. Also, pimecrolimus prevents the release of inflammatory cytokines and mediators from mast cells in vitro after stimulation by antigen/lgE.

Dosage forms of Pimecrolimus

FormRouteStrength
Creamtopical1 %
Creamtopical10 mg/g
Prescription Generics

false

International Brands

Elidel

Synonyms

33-Epi-chloro-33-desoxyascomycin Pimecrolimus

Manufacturers

Physicians Total Care, Inc.

CAS number

137071-32-0

UNII

7KYV510875

State

solid

Affected organisms

Humans and other mammals

Indication of Pimecrolimus

For treatment of mild to moderate atopic dermatitis.

Toxicity of Pimecrolimus

Side effects include burning sensation, irritation, pruritus, erythema, and skin infections, at the application site.

RX24 Drugs Disclaimer: before buying a Pimecrolimus on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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