Save up -80% on Pioglitazone
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Actos
|price without discount in nearest pharmacy. Price may vary.|
We offer free Actos coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Pioglitazone every time. What are you waiting for? Claim your prescription drug card now!
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Pioglitazone volume of distribution
The estimated volume of distribution in humans is 0.25 l/kg. Pioglitazone and all active metabolites are extensively bound to plasma protein (> 99%).
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Pioglitazone
Pioglitazone is used for the treatment of diabetes mellitus type 2. Pioglitazone selectively stimulates nuclear receptor peroxisone proliferator-activated receptor gamma (PPAR-gamma). It modulates the transcription of the insulin-sensitive genes involved in the control of glucose and lipid metabolism in the lipidic, muscular tissues and in the liver.
Pioglitazone mechanism of action
Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors increases the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. In this way, pioglitazone both enhances tissue sensitivity to insulin and reduces hepatic gluconeogenesis. Thus, insulin resistance associated with type 2 diabetes mellitus is improved without an increase in insulin secretion by pancreatic . cells.
Dosage forms of Pioglitazone
|Actoplus Met||15/850mg||56 Tablet||$121.00|
|Actoplus Met||15/850mg||112 Tablet||$219.35|
Accel Pharma Inc
Humans and other mammals
Indication of Pioglitazone
Treatment of Type II diabetes mellitus
Toxicity of Pioglitazone
Hypogycemia; LD sub50 /sub=mg/kg (orally in rat)
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