Save up -80% on Pirfenidone

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Esbriet

$9,088270 capsules/267 mg
price without discount in nearest pharmacy. Price may vary.

Claim your free Pirfenidone discount card

We offer free Pirfenidone coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Pirfenidone every time. What are you waiting for? Claim your prescription drug card now!

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Pirfenidone volume of distribution

RX Prescription
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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Pirfenidone

Pirfenidone is an orally active small molecule drug that may inhibit collagen synthesis, down regulate production of multiple cytokines and block fibroblast proliferation and stimulation in response to cytokines. Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver. It is being investigated by InterMune.

Pirfenidone mechanism of action

Pirfenidone is an orally active, small molecule that shows a wide range of biologic activity. In vitro evidence has shown that pirfenidone inhibits collagen synthesis, down-regulates profibrotic cytokines and decreases fibroblast proliferation. Pirfenidone leads to a reduction of TGF-beta2 mRNA levels and of the mature TGF-beta2 protein due to decreased expression and direct inhibition of the TGF-beta pro-protein convertase furin. In addition, pirfenidone reduces the protein levels of the matrix metalloproteinase (MMP)-11, a TGF-beta target gene and furin substrate involved in carcinogenesis.

Dosage forms of Pirfenidone

FormRouteStrength
Capsuleoral267 mg/1
Capsuleoral267 mg
Capsule, hardOral use267 mg

Prescription Generics

false

International Brands

Esbriet

Synonyms

Manufacturers

Hoffmann La Roche Limited

CAS number

53179-13-8

UNII

D7NLD2JX7U

State

solid

Affected organisms

Humans and other mammals

Indication of Pirfenidone

For the treatment of idiopathic pulmonary fibrosis (IPF).

Toxicity of Pirfenidone

Generally well tolerated with the most frequent side effects reported being photosensitivity rash and gastrointestinal symptoms.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Pirfenidone on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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