Save up -80% on Podofilox
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Condylox
|$307.34||1 bottle (3.5ml) 0.5% topical solution|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Condylox coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Podofilox every time. What are you waiting for? Claim your prescription drug card now!
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Podofilox volume of distribution
Small amounts of podofilox may be absorbed systemically following topical application. In a study in adults with anogenital warts caused by human papillomavirus, topical application of 0.05 mL of podofilox 0.5% solution to external genitalia did not result in detectable serum concentrations of the drug; however, topical application of 0.1-1.5mL of the solution resulted in peak serum concentrations of 1-17 ng/mL at 1-2 hours after application.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Podofilox
A lignan (lignans) found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
Podofilox mechanism of action
The exact mechanism of action is not well understood. It does appear, however, that it and its derivatives may bind and inhibit topoisomerase II during the late S and early G2 stage. The drug may bind and stabilize the temporary break caused by the enzyme. This disrupts the reparation of the break through which the double-stranded DNA passes, and consequently stops DNA unwinding and replication
Dosage forms of Podofilox
|Condylox Solution||0.50%||3.5mL Solution||$75.00|
Sanofi Aventis Canada Inc
Indication of Podofilox
For treatment of external genital warts ( iCondyloma acuminatum /i).
Toxicity of Podofilox
Topically applied Condyline (Podofilox Topical solution 0.5%) may be absorbed
systemically. It may cause systemic toxicity after oral ingestion. Neurotoxic reactions are
observed after oral doses exceeding 0.5 mg podofilox per kg body weight. For an adult this dose
corresponds to the equivalent of the content of two bottles of 3.5 mL Condyline.
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