Save up -80% on Pomalidomide
Note: this is a drug discount program, not an insurance plan.
2018 Price of Pomalyst
* price without discount in nearest pharmacy. Price may vary.
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Pomalidomide volume of distribution
Mean apparent volume of distribution (Vd/F), steady-state = 62 – 138 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Pomalidomide mechanism of action
Promalidomide is an immunomodulatory agent with antineoplastic activity. It is shown to inhibit the proliferation and induce apoptosis of various tumour cells. Furthermore, promalidomide enhances T cell and natural killer (NK) cell-mediated immunity and inhibited the production of pro-inflammatory cytokines, like TNF-alpha or IL-6, by monocytes. The primary target of promalidomide is thought to be the protein cereblon. It binds to this target and inhibits ubiquitin ligase activity. It is also a transcriptional inhibitor of COX2.
Dosage forms of Pomalidomide
Humans and other mammals
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