Save up -80% on Pomalidomide

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

Pharmacists and Patients support.

2018 Price of Pomalyst

$16,159

1mg

* price without discount in nearest pharmacy. Price may vary.

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Pomalidomide volume of distribution

Mean apparent volume of distribution (Vd/F), steady-state = 62 – 138 L

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What is Pomalidomide

Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.

Pomalidomide mechanism of action

Promalidomide is an immunomodulatory agent with antineoplastic activity. It is shown to inhibit the proliferation and induce apoptosis of various tumour cells. Furthermore, promalidomide enhances T cell and natural killer (NK) cell-mediated immunity and inhibited the production of pro-inflammatory cytokines, like TNF-alpha or IL-6, by monocytes. The primary target of promalidomide is thought to be the protein cereblon. It binds to this target and inhibits ubiquitin ligase activity. It is also a transcriptional inhibitor of COX2.

Dosage forms of Pomalidomide

DrugDosageQuantityPrice
Pomalyst1mg21 capsules$16,159
Pomalyst2mg21 capsules$15,730
Pomalyst3mg21 capsules$16,159
Pomalyst4mg21 capsules$16,156
Prescription Generics

false

International Brands

Pomalyst

Synonyms

Manufacturers

Celgene Corporation

CAS number

19171-19-8

UNII

D2UX06XLB5

State

solid

Affected organisms

Humans and other mammals

Indication of Pomalidomide

Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.

Toxicity of Pomalidomide

Most common adverse reactions ( 30%) included fatigue and asthenia, neutropenia, anemia, constipation, nausea, diarrhea, dyspnea, upper-respiratory tract infections, back pain and pyrexia.

RX24 Drugs Disclaimer: before buying a Pomalidomide on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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