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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Porfimer

Photofrin 75 mg vial

$3317.04

vial

* price without discount in nearest pharmacy. Price may vary.

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Porfimer volume of distribution

* 0.49 0.28 L/kg (2 mg/kg dose of porfimer sodium to 4 male cancer patients)

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What is Porfimer

The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in the United States.

Porfimer mechanism of action

Cellular damage caused by porfimer is a consequence of the propagation of radical reactions. Radical initiation may occur after porfimer absorbs light to form a porphyrin excited state. Spin transfer from porfimer to molecular oxygen may then generate singlet oxygen. Subsequent radical reactions can form superoxide and hydroxyl radicals. Tumor death also occurs through ischemic necrosis secondary to vascular occlusion that appears to be partly mediated by thromboxane A2 release.

Dosage forms of Porfimer

FormRouteStrength
Injection, powder, for solutionintravenous75 mg/31.8mL
Powder for solutionintravenous15 mg
Powder for solutionintravenous75 mg
Prescription Generics

false

International Brands

Photofrin

Synonyms

Dihaematoporphyrin Ether Dihematoporphyrin ether

Manufacturers

Concordia Laboratories Inc

CAS number

87806-31-3

UNII

Y3834SIK5F

State

solid

Affected organisms

Humans and other mammals

Indication of Porfimer

Indicated in the treatment of esophageal cancer.

Toxicity of Porfimer

RX24 Drugs Disclaimer: before buying a Porfimer on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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