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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Porfimer

Photofrin 75 mg vial



* price without discount in nearest pharmacy. Price may vary.

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Porfimer volume of distribution

* 0.49 0.28 L/kg (2 mg/kg dose of porfimer sodium to 4 male cancer patients)

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What is Porfimer

The purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins. It is used in photodynamic therapy (hematoporphyrin photoradiation); to treat malignant lesions with visible light and experimentally as an antiviral agent. It is the first drug to be approved in the use of photodynamic therapy in the United States.

Porfimer mechanism of action

Cellular damage caused by porfimer is a consequence of the propagation of radical reactions. Radical initiation may occur after porfimer absorbs light to form a porphyrin excited state. Spin transfer from porfimer to molecular oxygen may then generate singlet oxygen. Subsequent radical reactions can form superoxide and hydroxyl radicals. Tumor death also occurs through ischemic necrosis secondary to vascular occlusion that appears to be partly mediated by thromboxane A2 release.

Dosage forms of Porfimer

Injection, powder, for solutionintravenous75 mg/31.8mL
Powder for solutionintravenous15 mg
Powder for solutionintravenous75 mg
Prescription Generics


International Brands



Dihaematoporphyrin Ether Dihematoporphyrin ether


Concordia Laboratories Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Porfimer

Indicated in the treatment of esophageal cancer.

Toxicity of Porfimer

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