Save up -80% on Pramlintide

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Symlinpen

$939.831 carton (2 pens) 1.5ml
Price with discount in nearest pharmacy. Price may vary.

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We offer free Symlinpen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Pramlintide every time. What are you waiting for? Claim your prescription drug card now!

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Pramlintide volume of distribution

The absolute bioavailability of a single subcutaneous dose of pramlintide is approximately 30 to 40%. Pramlintide does not extensively bind to blood cells or albumin (approximately 40% of the drug is unbound in plasma).

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Pramlintide

Pramlintide is a relatively new adjunct treatment for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals. It is derived from amylin, a hormone that is released into the bloodstream, in a similar pattern as insulin, after a meal. Like insulin, amylin is deficient in individuals with diabetes.

Pramlintide mechanism of action

Pramlintide is an amlyinomimetic, a functional analog of the naturally occurring pancreatic hormone amylin. Amylin has activity in a number of gastrointestinal and glucodynamic systems, and by mimicking its activity, pramlintide acts to improve glycemic control through modulation of the rate of gastric emptying, prevention of post-prandial rise in glucagon levels, and by increasing sensations of satiety, thereby reducing caloric intake and potentiating weight loss. There appears to be at least three distinct receptor complexes that bind with high affinity to amylin. All three complexes contain the calcitonin receptor at the core, plus one of three Receptor activity-modifying proteins, RAMP1, RAMP2, or RAMP3.

Dosage forms of Pramlintide

FormRouteStrength
Injectionsubcutaneous1000 ug/mL

Prescription Generics

false

International Brands

Symlinpen

Synonyms

Manufacturers

Astra Zeneca Pharmaceuticals Lp

CAS number

151126-32-8

UNII

D3FM8FA78T

State

liquid

Affected organisms

Humans and other mammals

Indication of Pramlintide

For the treatment of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy.

Toxicity of Pramlintide

In large clinical trials, serum enzyme elevations were rare (<1%) during pramlintide/insulin therapy and no more common than with placebo and there were no reports of clinically apparent liver injury among treated patients. Since licensure, there have been no published case reports of hepatotoxicity due to pramlintide and the product label does not list liver injury as an adverse event. Thus, liver injury due to pramlintide must be rare, if it occurs at all.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Pramlintide on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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