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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Praziquantel

Praziquantel powder

$1.06

g

* price without discount in nearest pharmacy. Price may vary.

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Praziquantel volume of distribution

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What is Praziquantel

An anthelmintic used in most schistosome and many cestode infestations.

Praziquantel mechanism of action

Praziquantel works by causing severe spasms and paralysis of the worms’ muscles. This paralysis is accompanied – and probably caused – by a rapid Ca 2+ influx inside the schistosome. Morphological alterations are another early effect of praziquantel. These morphological alterations are accompanied by an increased exposure of schistosome antigens at the parasite surface. The worms are then either completely destroyed in the intestine or passed in the stool. An interesting quirk of praziquantel is that it is relatively ineffective against juvenile schistosomes. While initially effective, effectiveness against schistosomes decreases until it reaches a minimum at 3-4 weeks. Effectiveness then increases again until it is once again fully effective at 6-7 weeks. Glutathione S-transferase (GST), an essential detoxification enzyme in parasitic helminths, is a major vaccine target and a drug target against schistosomiasis. Schistosome calcium ion channels are currently the only known target of praziquantel.

Dosage forms of Praziquantel

FormRouteStrength
Tabletoral600 mg
Tablet, film coatedoral600 mg/1
Prescription Generics

false

International Brands

Biltricide

Synonyms

Biltricide

Manufacturers

Bayer Inc

CAS number

55268-74-1

UNII

6490C9U457

State

solid

Affected organisms

Indication of Praziquantel

For the treatment of infections due to all species of schistosoma.

Toxicity of Praziquantel

RX24 Drugs Disclaimer: before buying a Praziquantel on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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