Save up -80% on Pregabalin
Note: this is a drug discount program, not an insurance plan.
2018 Price of Pregabalin
Lyrica 200 mg capsule
* price without discount in nearest pharmacy. Price may vary.
We offer free Pregabalin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Pregabalin every time. What are you waiting for? Claim your prescription drug card now!
Pregabalin volume of distribution
|Act Pregabalin||Capsule||150 mg||Oral||Actavis Pharma Company|
|Lyrica||Capsule||50 mg/1||Oral||Unit Dose Services|
|Lyrica CR||Tablet, film coated, extended release||165 mg/1||Oral||Parke Davis Div Of Pfizer Inc|
|M-pregabalin||Capsule||150 mg||Oral||Mantra Pharma Inc|
|Pregabalin||Capsule||300 mg||Oral||Laboratoire Riva Inc|
|Pregabalin Capsules||Capsule||50 mg||Oral||Lupin Pharmaceuticals|
|Pregabalin Pfizer||Capsule||225 mg||Oral||Pfizer|
|Pregabalin-150||Capsule||150 mg||Oral||Sivem Pharmaceuticals Ulc|
|Sandoz Pregabalin||Capsule||50 mg||Oral||Sandoz Canada Incorporated|
Apparent volume of distribution, oral administration = 0.5 L/kg. Pregabalin has been shown to cross the placenta in rats and is present in the milk of lactating rats.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Pregabalin
Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by Pfizer under the trade name Lyrica. It is considered to have a dependence liability if misused, and is classified as a Schedule V drug in the U.S. (Wikipedia)
Pregabalin mechanism of action
Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. Although the mechanism of action of pregabalin is unknown, results with genetically modified mice and with compounds structurally related to pregabalin (such as gabapentin) suggest that binding to the alpha2-delta subunit may be involved in pregabalin’s antinociceptive and antiseizure effects in animal models. In vitro, pregabalin reduces the calcium-dependent release of several neurotransmitters, possibly by modulation of calcium channel function. Studies also suggest that the descending noradrenergic and serotonergic pathways originating from the brainstem may be involved with the mechanism of pregabalin. Interestingly, although pregabalin is a structural derivative of inhibitory neurotransmitter gamma-aminobutyric acid (GABA), it does not bind directly to GABA or benzodiazepine receptors. The sodium channels, opiate receptors, and cyclooxygenase enzymes are not involved with the mechanism of pregabalin. It is also inactive at serotonin and dopamine receptors and does not inhibit dopamine, serotonin, or noradrenaline reuptake.
Dosage forms of Pregabalin
|Lyrica 100 mg capsule||$2.88||capsule|
|Lyrica 150 mg capsule||$2.88||capsule|
|Lyrica 50 mg capsule||$2.88||capsule|
|Lyrica 75 mg capsule||$2.88||capsule|
|Lyrica 200 mg capsule||$2.75||capsule|
|Lyrica 225 mg capsule||$2.75||capsule|
|Lyrica 25 mg capsule||$2.75||capsule|
|Lyrica 300 mg capsule||$2.75||capsule|
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Act Pregabalin, Lyrica, Lyrica CR, M-pregabalin, Pregabalin, Pregabalin Capsules, Pregabalin Pfizer, Pregabalin-150, Sandoz Pregabalin
AS Medication Solutions, Actavis Pharma Company, Alembic Pharmaceuticals Limited, Bryant ranch prepack, Cardinal Health, Directrx, Dispensing Solutions, H.J. Harkins Company, Laboratoire Riva, Lake Erie Medical&Surgical Supply, Lupin Pharmaceuticals, Mantra Pharma Inc, Parke Davis Div Of Pfizer, Pd Rx Pharmaceuticals, Pfizer, Physicians Total Care, Pro Doc Limitee, Ranbaxy Inc, Rebel Distributors, Remedy Repack, Sandoz Canada Incorporated, Sanis Health Inc, Sivem Pharmaceuticals Ulc, St. Marys Medical Park Pharmacy, Stat Rx USA, U.S. Pharmaceuticals, Unit Dose Services
Humans and other mammals
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