Save up -80% on Procyclidine
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Price of Procyclidine
Pms-Procyclidine 0.5 mg/ml Elixir
* price without discount in nearest pharmacy. Price may vary.
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Procyclidine volume of distribution
What is Procyclidine
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism. (PubChem)
Procyclidine mechanism of action
The mechanism of action is unknown. It is thought that Procyclidine acts by blocking central cholinergic receptors, and thus balancing cholinergic and dopaminergic activity in the basal ganglia. Many of its effects are due to its pharmacologic similarities with atropine. Procyclidine exerts an antispasmodic effect on smooth muscle, and may produce mydriasis and reduction in salivation.
Dosage forms of Procyclidine
Humans and other mammals
Indication of Procyclidine
For the treatment of all forms of Parkinson’s Disease, as well as control of extrapyramidal reactions induced by antipsychotic agents.
Toxicity of Procyclidine
LD sub 50 /sub =60 mg/kg (IV in mice)
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