Save up -80% on Promethazine

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Phenergan

$7.0630 tablets/25 mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Promethazine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Promethazine every time. What are you waiting for? Claim your prescription drug card now!

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Promethazine volume of distribution

Promethazine is widely distributed in body tissues. Compared with other organs, lower concentrations of the drug are found in the brain, but this concentration is higher than the plasma concentration.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Promethazine

A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.

Promethazine mechanism of action

Like other H1-antagonists, promethazine competes with free histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscle. The relief of nausea appears to be related to central anticholinergic actions and may implicate activity on the medullary chemoreceptor trigger zone.

Dosage forms of Promethazine

Suppositoryrectal12.5 mg/1
Suppositoryrectal25 mg/1

Prescription Generics


International Brands

Dextromethorphan Hydrobromide and Promethazine Hydrochloride


(2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine 10-(2-Dimethylaminopropyl)phenothiazine



CAS number






Affected organisms

Humans and other mammals

Indication of Promethazine

For the treatment of allergic disorders, and nausea/vomiting.

Toxicity of Promethazine

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD sub 50 /sub =55mg/kg (I.V. in mice)

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Promethazine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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