Save up -80% on Prucalopride
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2018 Price of Prucalopride
* price without discount in nearest pharmacy. Price may vary.
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Prucalopride volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Prucalopride
Prucalopride (brand name Resolor, developed by Johnson – Johnson and licensed to Movetis) is a drug acting as a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements. Prucalopride was approved for use in Europe in 2009 and in Canada (named Resotran) on December 7, 2011 but it has not been approved by the Food and Drug Administration for use in the United States. The drug has also been tested for the treatment of chronic intestinal pseudo-obstruction.
Prucalopride mechanism of action
Prucalopride (PRU) is a selective high affinity 5-HT4 agonist, which are involved in initiating peristalsis. Prucalopride alters colonic motility patterns via serotonin 5-HT4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation.
Dosage forms of Prucalopride
Humans and other mammals
Indication of Prucalopride
Investigated for use/treatment in constipation, ileus, and pediatric indications.
Toxicity of Prucalopride
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