Save up -80% on Pyrimethamine

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Pyrimethamine

Pyrimethamine powder

$8.88

g

* price without discount in nearest pharmacy. Price may vary.

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Pyrimethamine volume of distribution

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What is Pyrimethamine

One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.

Pyrimethamine mechanism of action

Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication. This leads to failure of nuclear division at the time of schizont formation in erythrocytes and liver.

Dosage forms of Pyrimethamine

FormRouteStrength
Tabletoral25 mg/1
Tabletoral25 mg
Tabletoral
Prescription Generics

false

International Brands

Daraprim

Synonyms

2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidine

Manufacturers

Amedra Pharmaceuticals LLC

CAS number

58-14-0

UNII

Z3614QOX8W

State

solid

Affected organisms

Plasmodium

Indication of Pyrimethamine

For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine

Toxicity of Pyrimethamine

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