Save up -80% on Quinidine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Quinora
|$17.58||90 tablets/200 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Quinidine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Quinidine every time. What are you waiting for? Claim your prescription drug card now!
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Quinidine volume of distribution
Many of the metabolites appear to be pharmacologically active. Typical ranges for kinetic properties of quinidine in healthy persons are: apparent volume of distribution 2.0 to 3.5 litres/kg: elimination half-life 5 to 12 hours; clearance, 2.5 to 5.0ml/min/kg.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Quinidine
An optical isomer of quinine, extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
Quinidine mechanism of action
Quinidine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers. Quinidine may also act on the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito.
Dosage forms of Quinidine
|Capsule, gelatin coated||oral|
Apo Quinidine Tab 200mg
Humans and other mammals
Indication of Quinidine
For the treatment of ventricular pre-excitation and cardiac dysrhythmias
Toxicity of Quinidine
Toxic effects appear within 2 – 4 hours after ingestion but the delay may vary according to the quinidine salt and to the preparation forms. Symptoms may include disturbances of cardiac rhythm (especially in patients with underlying cardiovascular disease), neurotoxicity and respiratory depression. Diagnosis: Cardiac disturbances: circulatory arrest, shock, conduction disturbances, ventricular arrhythmias, ECG changes, Neurological symptoms: tinnitus, drowsiness, syncope, coma, convulsions, delirium.
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