Save up -80% on Rabeprazole
Note: this is a drug discount program, not an insurance plan.
Price of Rabeprazole
Pariet 20 mg Enteric-Coated Tablet
* price without discount in nearest pharmacy. Price may vary.
We offer free Rabeprazole coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your coupon in most local pharmacies to get a discount on Rabeprazole. Claim your prescription drug card now!
Rabeprazole volume of distribution
What is Rabeprazole
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug – in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Rabeprazole mechanism of action
Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H sup+ /sup/K sup+ /supATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds.
Dosage forms of Rabeprazole
|Tablet, coated||oral||20 mg/1|
|Capsule, delayed release||oral||10 mg/1|
|Capsule, delayed release||oral||5 mg/1|
Bgp Pharma Ulc
Humans and other mammals
Indication of Rabeprazole
For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use.
Toxicity of Rabeprazole
Disclaimer: before buying a Rabeprazole on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.