Save up -80% on Ramelteon

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ramelteon

Rozerem 8 mg tablet

$5.17

tablet

* price without discount in nearest pharmacy. Price may vary.

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Ramelteon volume of distribution

* 73.6 L

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What is Ramelteon

Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.

Ramelteon mechanism of action

Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT sub 1 /sub and MT sub 2 /sub receptors, and lower selectivity for the MT sub 3 /sub receptor. Melatonin production is concurrent with nocturnal sleep, meaning that an increase in melatonin levels is related to the onset of self-reported sleepiness and an increase in sleep propensity. MT sub 1 /sub receptors are believed to be responsible for regulation of sleepiness and facilitation of sleep onset, and MT sub 2 /sub receptors are believed to mediate phase-shifting effects of melatonin on the circadian rhythm. While MT sub 1 /sub and MT sub 2 /sub receptors are associated with the sleep-wake cycle, MT sub 3 /sub has a completely different profile, and therefore is not likely to be involved in the sleep-wake cycle. Remelteon has no appreciable affinity for the gamma-aminobutyric acid (GABA) receptor complex or receptors that bind neuropeptides, cytokines, serotonin, dopamine, norepinephrine, acetylcholine, or opiates.

Dosage forms of Ramelteon

FormRouteStrength
Tablet, film coatedoral8 mg/1
Prescription Generics

false

International Brands

Rozerem

Synonyms

Rozerem

Manufacturers

Lake Erie Medical DBA Quality Care Products LLC

CAS number

196597-26-9

UNII

901AS54I69

State

solid

Affected organisms

Humans and other mammals

Indication of Ramelteon

For the treatment of insomnia characterized by difficulty with sleep onset.

Toxicity of Ramelteon

RX24 Drugs Disclaimer: before buying a Ramelteon on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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