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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Reserpine

Reserpine 0.25 mg tablet

$1.52

tablet

* price without discount in nearest pharmacy. Price may vary.

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Reserpine volume of distribution

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What is Reserpine

An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.

Reserpine mechanism of action

Reserpine’s mechanism of action is through inhibition of the ATP/Mg sup 2+ /sup pump responsible for the sequestering of neurotransmitters into storage vesicles located in the presynaptic neuron. The neurotransmitters that are not sequestered in the storage vesicle are readily metabolized by monoamine oxidase (MAO) causing a reduction in catecholamines.

Dosage forms of Reserpine

FormRouteStrength
Tabletoral.25 mg
Tabletoral.1 mg/1
Tabletoral.25 mg/1
Prescription Generics

false

International Brands

Hydropres 25 Tab

Synonyms

(-)-Reserpine ()-reserpine

Manufacturers

Merck Frosst Canada Cie, Merck Frosst Canada Co.

CAS number

50-55-5

UNII

8B1QWR724A

State

solid

Affected organisms

Humans and other mammals

Indication of Reserpine

Foe the treatment of hypertension

Toxicity of Reserpine

Possible human carcinogen. May cause reproductive harm. ORL-RAT LD sub 50 /sub 420 mg/kg; IPR-RAT LD sub 50 /sub 44 mg/kg; IVN-RAT LD sub 50 /sub 15 mg/kg; ORL-MUS LD sub 50 /sub 200 mg/kg; SCU-MUS LD sub 50 /sub 52 mg/kg; IPR-RBT LD sub 50 /sub 7 mg/kg

RX24 Drugs Disclaimer: before buying a Reserpine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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