Save up -80% on Retapamulin
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2018 Price of Retapamulin
Altabax 1% ointment
* price without discount in nearest pharmacy. Price may vary.
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Retapamulin volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Retapamulin
Retapamulin is a topical antibiotic developed by GlaxoSmithKline. It was approved by the United States Food and Drug Administration in April 2007 for the treatment of bacterial skin infections such as impetigo. It is marketed as an ointment under the name brand Altabax.
Retapamulin mechanism of action
Retapamulin is a bacterial protein synthesis inhibitor belonging to a class of compounds called pleuromutilins. These compounds inhibit the initiation of protein synthesis by binding to a specific site on the 50S subunit of bacterial ribosome (domain V of 23S rRNA). This binding site involves ribosomal protein L3 and is in the region of the ribosomal P site and peptidyl transferase center. By virtue of binding to this site, pleuromutilins inhibit peptidyl transfer, block P-site interactions, and prevent the normal formation of active 50S ribosomal subunits.
Dosage forms of Retapamulin
Glaxo Smith Kline Llc
Indication of Retapamulin
For use in adults and pediatric patients aged 9 months and older for the topical treatment of impetigo (up to 100 cm sup2 /sup in total area in adults or 2% total body surface area in pediatric patients aged 9 months or older) due to Staphylococcus aureus (methicillin-susceptible isolates only) or Streptococcus pyogenes.
Toxicity of Retapamulin
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