Save up -80% on Rilpivirine

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Edurant

$1,04430 tablets/25 mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Rilpivirine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Rilpivirine every time. What are you waiting for? Claim your prescription drug card now!

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Rilpivirine volume of distribution

The average volume of distribution was 401 liters

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About RX24Drugs

2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

savings

Total savings $4,735,080

What is Rilpivirine

Rilpivirine is non-nucleoside reverse transcriptase inhibitor (NNRTI) which is used for the treatment of HIV-1 infections in treatment-naive patients. It is a diarylpyrimidine, a class of molecules that resemble pyrimidine nucleotides found in DNA. Because of its flexible chemical structure, resistance of rilpivirine is less likely to develop than other NNRTI’s. FDA approved on May 20, 2011.

Rilpivirine mechanism of action

Rilpivirine is an NNRTI which binds to reverse transcriptase which results in a block in RNA and DNA- dependent DNA polymerase activities. One such activity is HIV-1 replication. Intracellular phosphorylation is not necessary for its antiviral activity. Because of the structure of rilpivirine is flexible around the aromatic rings, the molecule can have multiple conformations so that can bind to residues in the reverse transcriptase enzyme which have a lower mutation rate.

Dosage forms of Rilpivirine

FormRouteStrength
Tabletoral
Tablet, film coatedoral
Film-coated tablet page 1 of 1Oral use25 mg

Prescription Generics

false

International Brands

Complera

Synonyms

4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile

Manufacturers

A S Medication Solutions

CAS number

500287-72-9

UNII

FI96A8X663

State

solid

Affected organisms

Human Immunodeficiency Virus

Indication of Rilpivirine

Treatment of HIV-1 infections in treatment-naive patients with HIV-1 RNA 100,000 copies/mL in combination with at least 2 other antiretroviral agents.

Toxicity of Rilpivirine

Oral, mouse: LD50 = 300 mg/kg; Oral, rabbit: LD50 = 3200 mg/kg; Oral, rat: LD50 = 980 mg/kg.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Rilpivirine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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