Save up -80% on Risedronate

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Risedronate

Actonel with calcium tablet

$3.92

tablet

* price without discount in nearest pharmacy. Price may vary.

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Risedronate volume of distribution

* 13.8 L/kg

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What is Risedronate

Risedronate is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget’s disease of bone.

Risedronate mechanism of action

The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Risedronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.

Dosage forms of Risedronate

FormRouteStrength
Tabletoral150 mg
Tabletoral30 mg
Tabletoral35 mg
Prescription Generics

false

International Brands

Actonel

Synonyms

Acide risedroniqe Acido risedronico

Manufacturers

Warner Chilcott (US), LLC

CAS number

105462-24-6

UNII

KM2Z91756Z

State

solid

Affected organisms

Humans and other mammals

Indication of Risedronate

For the treatment of Paget’s disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis

Toxicity of Risedronate

Side effects include abdominal pain, anxiety, back pain, belching, bladder irritation, bone disorders and pain, bronchitis, bursitis, cataracts, chest pain, colitis, constipation, depression, diarrhea, difficulty breathing, dizziness, dry eyes, eye infection, flu-like symptoms, gas, headache, high blood pressure, infection, insomnia, itching, joint disorders and pain, leg cramps, muscle pain, muscle weakness, nausea, neck pain, nerve pain, pain, pneumonia, rash, ringing in ears, sinus problems, sore throat, stomach bleeding, stuffy or runny nose, swelling, tendon problems, tumor, ulcers, urinary tract infection, vertigo, vision problems, and weakness.

RX24 Drugs Disclaimer: before buying a Risedronate on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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