Save up -80% on Risedronate
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Actonel
|price without discount in nearest pharmacy. Price may vary.|
We offer free Actonel coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Risedronate every time. What are you waiting for? Claim your prescription drug card now!
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Risedronate volume of distribution
Mean absolute oral bioavailability of the 30-mg tablet is 0.63%. Food alters absorption; drug should be taken at least 30 minutes before breakfast. Distribution: The mean steady state volume of distribution is 6.3 L/kg. Plasma protein-binding is about 24%.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Risedronate
Risedronate is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget’s disease of bone.
Risedronate mechanism of action
The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Risedronate also targets farnesyl pyrophosphate (FPP) synthase. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway. Inhibition of this enzyme in osteoclasts prevents the biosynthesis of isoprenoid lipids (FPP and GGPP) that are essential for the post-translational farnesylation and geranylgeranylation of small GTPase signalling proteins. This activity inhibits osteoclast activity and reduces bone resorption and turnover. In postmenopausal women, it reduces the elevated rate of bone turnover, leading to, on average, a net gain in bone mass.
Dosage forms of Risedronate
Acide risedroniqe Acido risedronico
Warner Chilcott (US), LLC
Humans and other mammals
Indication of Risedronate
For the treatment of Paget’s disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis
Toxicity of Risedronate
Side effects include abdominal pain, anxiety, back pain, belching, bladder irritation, bone disorders and pain, bronchitis, bursitis, cataracts, chest pain, colitis, constipation, depression, diarrhea, difficulty breathing, dizziness, dry eyes, eye infection, flu-like symptoms, gas, headache, high blood pressure, infection, insomnia, itching, joint disorders and pain, leg cramps, muscle pain, muscle weakness, nausea, neck pain, nerve pain, pain, pneumonia, rash, ringing in ears, sinus problems, sore throat, stomach bleeding, stuffy or runny nose, swelling, tendon problems, tumor, ulcers, urinary tract infection, vertigo, vision problems, and weakness.
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