Save up -80% on Ritonavir
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Price of Ritonavir
Norvir 100 mg softgel cap
* price without discount in nearest pharmacy. Price may vary.
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Ritonavir volume of distribution
What is Ritonavir
An HIV protease inhibitor that works by interfering with the reproductive cycle of HIV. (PubChem)
Ritonavir mechanism of action
Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.
Dosage forms of Ritonavir
Human Immunodeficiency Virus
Indication of Ritonavir
Indicated in combination with other antiretroviral agents for the treatment of HIV-infection.
Toxicity of Ritonavir
Human experience of acute overdose with ritonavir is limited. One patient in clinical trials took ritonavir 1500 mg/day for two days. The patient reported paresthesias which resolved after the dose was decreased. A post-marketing case of renal failure with eosinophilia has been reported with ritonavir overdose. The approximate lethal dose was found to be greater than 20 times the related human dose in rats and 10 times the related human dose in mice.
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