Save up -80% on Rivastigmine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Exelon
|$125.66||30 patches 9.5mg/24 hours|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Rivastigmine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Rivastigmine every time. What are you waiting for? Claim your prescription drug card now!
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Rivastigmine volume of distribution
Rivastigmine is widely distributed throughout the body with a volume of distribution in the range of 1.8-2.7 L/kg. Rivastigmine penetrates the blood brain barrier, reaching CSF peak concentrations in 1.4-2.6 hours. Mean AUC1-12hr ratio of CSF/plasma averaged 40 ± 0.5% following 1-6 mg BID doses.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Rivastigmine
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Rivastigmine mechanism of action
Rivastigmine is a carbamate derivative that is structurally related to physostigmine, but not to donepezil and tacrine. The precise mechanism of rivastigmine has not been fully determined, but it is suggested that rivastigmine binds reversibly with and inactivates chlolinesterase (eg. acetylcholinesterase, butyrylcholinesterase), preventing the hydrolysis of acetycholine, and thus leading to an increased concentration of acetylcholine at cholinergic synapses. The anticholinesterase activity of rivastigmine is relatively specific for brain acetylcholinesterase and butyrylcholinesterase compared with those in peripheral tissues.
Dosage forms of Rivastigmine
|Exelon Patch||4.6mg/24hr||90 Patch||$312.95|
|Exelon Patch||9.5mg/24hr||60 Patch||$214.50|
|Exelon Patch||13.3mg/24hr||30 Patch||$189.00|
(S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate Ena 713 Free Base
Humans and other mammals
Indication of Rivastigmine
For the treatment of mild to moderate dementia associated with Parkinson‘s disease or of the Alzheimer’s type.
Toxicity of Rivastigmine
Rivastigmine, which has been approved by the US Food and Drugs Administration for the treatment of Alzheimer’s disease, is a non-competitive reversible inhibitor of acetylcholinesterase. A case of rivastigmine toxicity at a dose of 90 mg, with evidence of respiratory depression.
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