Save up -80% on Roflumilast
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Daliresp
|$366||30 tablets/500 mcg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Roflumilast coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Roflumilast every time. What are you waiting for? Claim your prescription drug card now!
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Roflumilast volume of distribution
Roflumilast has a Vd of 2.9L/kg with a dose of 500mcg. Permeability of roflumilast across the blood-brain barrier appears to be poor in rat studies.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Roflumilast
Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. Due to its selective inhibition of the PDE4 isoenzyme in lung cells, roflumilast is indicated for the management of chronic obstrtuctive pulmonary disease (COPD) exacerbations. Treatment with Roflumilast is associated with an increase in psychiatric adverse reactions, including suicide and suicidal attempts.
Roflumilast mechanism of action
Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor which, due to its selective inhibition of the PDE4 isoenzyme, has potential antiinflammatory and antimodulatory effects in the pulmonary system. It is thought that the increased levels of intracellular cyclic AMP are responsible for the therapeutic actions of Roflumilast.
Dosage forms of Roflumilast
|Film-coated tablet||Oral use||500 g|
Astra Zeneca Pharmaceuticals Lp
Humans and other mammals
Indication of Roflumilast
Roflumilast is indicated as a treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis and a history of exacerbations. Roflumilast is not a bronchodilator and is not indicated for the relief of acute bronchospasm.
Toxicity of Roflumilast
Headache, weight loss, GI upset, insomnia, and loose stools.
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