Save up -80% on Rosiglitazone

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Rosiglitazone

Avandia 2 mg tablet

$3.22tablet
price without discount in nearest pharmacy. Price may vary.

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We offer free Rosiglitazone coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Rosiglitazone every time. What are you waiting for? Claim your prescription drug card now!

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Rosiglitazone volume of distribution

* 17.6 L (oral volume of distribution Vss/F) * 13.5 L (population mean, pediatric patients)

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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Rosiglitazone

Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor class of the peroxisome proliferator-activated receptors (PPARs), specifically PPAR.. Rosiglitazone is a selective ligand of PPAR., and has no PPAR.-binding action. Apart from its effect on insulin resistance, it appears to have an anti-inflammatory effect: nuclear factor kappa-B (NF.B) levels fall and inhibitor (I.B) levels increase in patients on rosiglitazone. Recent research has suggested that rosiglitazone may also be of benefit to a subset of patients with Alzheimer’s disease not expressing the ApoE4 allele. This is the subject of a clinical trial currently underway.

Rosiglitazone mechanism of action

Rosiglitazone acts as a highly selective and potent agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors regulates the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. In this way, rosiglitazone enhances tissue sensitivity to insulin.

Dosage forms of Rosiglitazone

FormRouteStrength
Tabletoral2.0 mg
Tabletoral4.0 mg
Tabletoral8.0 mg

Prescription Generics

true

International Brands

Apo-rosiglitazone

Synonyms

()-5-(p-(2-(methyl-2-pyridylamino)ethoxy)benzyl)-2,4-thiazolidinedione (RS)-5-{4-(2-(Methyl-2-pyridylamino)ethoxy)benzyl}-2,4-thiazolidinedion

Manufacturers

Apotex Inc

CAS number

122320-73-4

UNII

05V02F2KDG

State

solid

Affected organisms

Humans and other mammals

Indication of Rosiglitazone

Rosiglitazone is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Toxicity of Rosiglitazone

Side effects include fluid retention, congestive heart failure (CHF), liver disease

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Rosiglitazone on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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