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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Rufinamide

$

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Rufinamide volume of distribution

Rufinamide was evenly distributed between erythrocytes and plasma. The apparent volume of distribution is dependent upon dose and varies with body surface area. The apparent volume of distribution was about 50 L at 3200 mg/day. Volume of distribution is similar between adults and children and is non-linear.

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What is Rufinamide

Rufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. Clinical trials suggest its efficacy in the treatment of partial seizures.

Rufinamide mechanism of action

Rufinamide is a triazole derivative antiepileptic that prolongs the inactive state of voltage gated sodium channels thus stabilizing membranes, ultimately blocking the spread of partial seizure activity.

Dosage forms of Rufinamide

FormRouteStrength
Suspensionoral40 mg
Suspensionoral40 mg/mL
Tabletoral100 mg
Prescription Generics

false

International Brands

Banzel

Synonyms

Banzel RUF 331

Manufacturers

Eisai Inc.

CAS number

106308-44-5

UNII

WFW942PR79

State

solid

Affected organisms

Humans and other mammals

Indication of Rufinamide

Adjunct therapy for treatment of seizures associated with Lennox-Gastaut syndrome.

Toxicity of Rufinamide

The most commonly observed adverse reactions ( 10% and greater than placebo) were headache, dizziness, fatigue, somnolence, and nausea.

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