Save up -80% on Salmon Calcitonin

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Miacalcin

$305.881 nasal spray (3.7ml) 200iu
Price with discount in nearest pharmacy. Price may vary.

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Salmon Calcitonin volume of distribution

The apparent volume of distribution is 0.15-0.3 L/kg. It appears that calcitonin-salmon cannot cross the placental barrier and its passage to the cerebrospinal fluid or to breast milk has not been determined.

FormRouteStrength
Liquidintramuscular; subcutaneous200 unit
Solutionnasal200 unit
Solutionintramuscular; subcutaneous200 unit
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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Salmon Calcitonin

Synthetic peptide, 32 residues long formulated as a nasal spray.

Salmon Calcitonin mechanism of action

Calcitonin binds to the calcitonin receptor (found primarily in osteoclasts) which then enhances the production of vitamin D producing enzymes (25-hydroxyvitamine D-24-hydroxylase), leading to greater calcium retention and enhanced bone density. Binding of calcitonin to its receptor also activates adenylyl cyclase and the phosphatidyl-inositol-calcium pathway.

Dosage forms of Salmon Calcitonin

DrugDosageQuantityPrice
Miacalcin3.7ml200iu/spray$43.18

Prescription Generics

true

International Brands

Apo-calcitonin Injectable

Synonyms

Calcimar Calcitonin (Salmon Synthetic)

Manufacturers

Apotex Inc

CAS number

47931-85-1

UNII

7SFC6U2VI5

State

liquid

Affected organisms

Humans and other mammals

Indication of Salmon Calcitonin

Used in the treatment of symptomatic Paget’s disease for patients unresponsive to alternate treatments or intolerant to such treatments. In addition, it is used in emergency situations when serum calcium levels must be decreased quickly until the underlying condition is identified. It can also be added to existing therapeutic regimens for hypercalcemia such as intravenous fluids and furosemide, oral phosphate or corticosteroids, or other agents. Calcitonin can be used in patients with azotemia and cases where intravenous fluids would be contraindicated due to limited cardiac reserves. Also for the treatment of post-menopausal osteoporosis in women more than 5 years post-menopause.

Toxicity of Salmon Calcitonin

Salmon calcitonin was shown to inhibit lactation in animals and is not recommend in nursing mothers. While research in animals have shown a decrease in fetal weight, no studies have yet shown similar results in humans. It is recommended however to proceed carefully when administering salmon calcitonin to pregnant women and consider if the benefits outweigh the risks. Because of its protein nature, salmon calcitonin may provoke an allergy reaction (bronchospams and swelling of the tongue/throat) that can turn into a full-blown anaphylactic response. The manufacturer also reports an increase in the risk of malignancies from oral route (0.7%) to intranasal route (2.4%) compared to placebo. The same may apply to IV, IM and SC routes since the systemic exposure is higher in those cases. Nausea is noticeable in some patients but tends to decrease with continued administration. Rhinitis, headaches and back pain have also been reported among others.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Salmon Calcitonin on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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