Save up -80% on Sargramostim

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Leukine

$527.872 vials/250mcg
price without discount in nearest pharmacy. Price may vary.

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We offer free Leukine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Sargramostim every time. What are you waiting for? Claim your prescription drug card now!

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Sargramostim volume of distribution

Sargramostim is administered intravenously (IV) or subcutaneously. Following IV administration, the observed volume of distribution was 96.8%. In healthy volunteers, the mean terminal elimination half-life values were 3.84 and 1.4 hours and the mean clearance values were 17.2 and 23 L/hour following sargramostim 500 mcg IV (over 2 hours) and sargramostim as a subcutaneous injection, respectively. Sargramostim appears to be metabolized to small peptides and amino acids.

FormRouteStrength
Injection, powder, for solutionintravenous; subcutaneous250 ug/mL
Liquidintravenous; subcutaneous500 ug/mL
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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Sargramostim

Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.

Sargramostim mechanism of action

Sargramostim binds to the Granulocyte-macrophage colony stimulating factor receptor (GM-CSF-R-alpha or CSF2R) which stimulates a JAK2 STAT1/STAT3 signal transduction pathway. This leads to the production of hemopoietic cells and neutrophils

Dosage forms of Sargramostim

DrugDosageQuantityPrice
Leukine250mcg30 vials$7,580

Prescription Generics

false

International Brands

Leukine

Synonyms

GM-CSF

Manufacturers

Sanofi Aventis U.S. Llc

CAS number

123774-72-1

UNII

5TAA004E22

State

liquid

Affected organisms

Humans and other mammals

Indication of Sargramostim

For the treatment of cancer and bone marrow transplant

Toxicity of Sargramostim

Among patients with unresectable stage III or IV melanoma, treatment with sargramostim plus ipilimumab, compared to ipilimumab alone, resulted in longer overall survival and lower toxicity, but no difference in progression free survival. These findings require confirmation in larger sample sizes and longer follow up.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Sargramostim on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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