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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Ex-Lax

$6.8530 tablets/15mg
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Senna glycoside volume of distribution

Senna is administered orally and rectally. The pharmacokinetics of senna are not well characterized. There is insufficient evidence of distribution into breast milk, but amounts are unlikely to be a problem. Absorbed anthraquinones are believed to be metabolized by the liver and may be excreted via the bile in feces, and, possibly, in urine.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Senna glycoside

Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. The medication is taken by mouth or via the rectum. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth. It is a weaker laxative than bisacodyl or castor oil.

Senna glycoside mechanism of action

Senna derivatives are a type of stimulant laxative and are of the anthraquinone type. While its mechanism of action is not entirely clear, senna is thought to act by increasing fluid secretion within and contraction of the large intestine.

Dosage forms of Senna glycoside

Sennosides8.6mg60 tablets$4
Sennosides15mg30 tablets$5.50
Sennosides25mg90 tablets$16.58

Prescription Generics


International Brands

Agarol Extra Strength Chewable Laxative Tablets


Senna Sennoside


Numark Laboratories, Inc.

CAS number





Affected organisms

Indication of Senna glycoside

For the treatment of constipation.

Toxicity of Senna glycoside

Significant increases in the incidences of epithelial hyperplasia of the colon and cecum were observed at 10,000 ppm in p53+/− males and females, and the incidence of hyperplasia of the colon was significantly increased at 3,000 ppm in females. In conclusion, the large intestine was the major target of senna-induced toxicity in both wild-type and the p53+/− mouse model.

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