Save up -80% on Sevelamer
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Renvela
|Price with discount in nearest pharmacy. Price may vary.|
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Sevelamer volume of distribution
Total urine and feces were collected at intervals up to 72 hours post dose, and tissues were obtained at the time of sacrifice. In the clinical trial, subjects received a single oral dose of (14)C sevelamer following 28 days of pretreatment with unlabelled sevelamer. Blood, urine and feces samples were collected at intervals up to 96 hours.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Sevelamer
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. When taken with meals, sevelamer binds to dietary phosphate and prevents its absorption. It is marketed by Genzyme under the trade name Renagel.
Sevelamer mechanism of action
Sevelamer prevents hyperphosphatemia by binding to dietary phosphate in the gut, preventing its absorption and thus decreasing serum parathyroid hormone levels.
Dosage forms of Sevelamer
|Sevelamer Hydrochloride||400mg||60 Tablet||$78.00|
|Sevelamer Hydrochloride||800mg||30 Tablet||$53.00|
|Sevelamer Carbonate||800mg||100 Tablet||$109.10|
Aphena Pharma Solutions Tennessee, Llc
Humans and other mammals
Indication of Sevelamer
For the control of serum phosphorus in patients with Chronic Kidney Disease (CKD) on hemodialysis.
Toxicity of Sevelamer
Sevelamer has been given to normal healthy volunteers in doses of up to 14 grams per day for eight days with no adverse effects. Sevelamer has been given in average doses up to 13 grams per day to hemodialysis patients. There are no reported overdosages of sevelamer in patients. Since sevelamer is not absorbed, the risk of systemic toxicity is low.
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What is Renvela?
Renvela is a phosphate binder. Renvela helps prevent hypocalcemia (low levels of calcium in the body) caused by elevated phosphorus. Renvela is used to control phosphorus levels in people with chronic kidney disease who are on dialysis.
You should not take Renvela if you have a bowel obstruction. Before taking Renvela, tell your doctor if you have severe constipation, a blockage in your intestines, stomach or intestinal disorders, problems with swallowing, or if you have recently had surgery on your stomach or intestines. Avoid taking any other medicines for 1 hour before or 3 hours after taking Renvela. Sevelamer can bind with other drugs and makes them less effective. Before taking this medicine, tell your doctor if you are taking Ciprofloxacin (Cipro), a medicine with a heart rhythm, or seizures. Do not take calcium or other mineral supplements without the advice of a doctor. Use only a certain type of calcium or mineral supplement recommended by your doctor.