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Price of Sevelamer
Renagel 400 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Sevelamer volume of distribution
What is Sevelamer
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. When taken with meals, sevelamer binds to dietary phosphate and prevents its absorption. It is marketed by Genzyme under the trade name Renagel.
Sevelamer mechanism of action
Sevelamer prevents hyperphosphatemia by binding to dietary phosphate in the gut, preventing its absorption and thus decreasing serum parathyroid hormone levels.
Dosage forms of Sevelamer
Aphena Pharma Solutions Tennessee, Llc
Humans and other mammals
Indication of Sevelamer
For the control of serum phosphorus in patients with Chronic Kidney Disease (CKD) on hemodialysis.
Toxicity of Sevelamer
Sevelamer has been given to normal healthy volunteers in doses of up to 14 grams per day for eight days with no adverse effects. Sevelamer has been given in average doses up to 13 grams per day to hemodialysis patients. There are no reported overdosages of sevelamer in patients. Since sevelamer is not absorbed, the risk of systemic toxicity is low.
Disclaimer: before buying a Sevelamer on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.