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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Sevoflurane

Ultane 250 ml pen bottle

$1.16

ml

* price without discount in nearest pharmacy. Price may vary.

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Sevoflurane volume of distribution

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What is Sevoflurane

Sevoflurane (2,2,2-trifluoro-1-(trifluoromethyl)ethyl fluoromethyl ether), also called fluoromethyl, is a sweet-smelling, non-flammable, highly fluorinated methyl isopropyl ether used for induction and maintenance of general anesthesia. Together with desflurane, it is replacing isoflurane and halothane in modern anesthesiology. (Wikipedia)

Sevoflurane mechanism of action

Sevoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Sevoflurane also activates calcium dependent ATPase in the sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. It also appears to bind the D subunit of ATP synthase and NADH dehydogenase and also binds to the GABA receptor, the large conductance Ca sup2+ /sup activated potassium channel, the glutamate receptor, and the glycine receptor.

Dosage forms of Sevoflurane

FormRouteStrength
Liquidinhalation99.97 %
Liquidrespiratory (inhalation)1 mL/mL
Liquidrespiratory (inhalation)250 mL/250mL
Prescription Generics

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International Brands

Sevoflurane

Synonyms

1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane Sevofluran

Manufacturers

Piramal Critical Care Inc

CAS number

28523-86-6

UNII

38LVP0K73A

State

liquid

Affected organisms

Humans and other mammals

Indication of Sevoflurane

Used for induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.

Toxicity of Sevoflurane

LC sub50 /sub=49881 ppm/hr (rat), LD sub50 /sub=10.8 g/kg (rat)

RX24 Drugs Disclaimer: before buying a Sevoflurane on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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