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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Sibutramine

Meridia 5 mg capsule

$4.0

capsule

* price without discount in nearest pharmacy. Price may vary.

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What is Sibutramine

Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines. Sibutramine is classified as a Schedule IV controlled substance in the United States. In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.

Sibutramine mechanism of action

Sibutramine produces its therapeutic effects by inhibition of norepinephrine (NE), serotonin (5-hydroxytryptamine, 5-HT), and to a lesser extent, dopamine reuptake at the neuronal synapse. By inhibiting the reuptake of these neurotransmitters, sibutramine promotes a sense of satiety and decrease in appetite, thereby reducing food intake. Data from animal studies also suggest that sibutramine may also increase energy expenditure through thermogenic effects in both the basal and fed states, but this has not been confirmed in humans. Sibutramine and its major pharmacologically active metabolites (M1 and M2) do not act via release of monoamines.

Dosage forms of Sibutramine

FormRouteStrength
Capsuleoral10 mg
Capsuleoral15 mg
Prescription Generics

true

International Brands

Apo-sibutramine

Synonyms

Butramin Sibutramina

Manufacturers

Apotex Inc

CAS number

106650-56-0

UNII

WV5EC51866

State

solid

Affected organisms

Humans and other mammals

Indication of Sibutramine

For the treatment of obesity.

Toxicity of Sibutramine

Side effects include dry mouth, anorexia, insomnia, constipation and headache.

RX24 Drugs Disclaimer: before buying a Sibutramine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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