Save up -80% on Silodosin
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Rapaflo
|$263.73||30 capsules/8 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Rapaflo coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Silodosin every time. What are you waiting for? Claim your prescription drug card now!
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Silodosin volume of distribution
Silodosin has a volume of distribution of 0.81 l/kg and is approximately 95% bound to plasma proteins, while binding of silodosin glucuronide is approximately 92%
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Silodosin
Silodosin is an 1-adrenoceptor antagonist that is selective for the prostate. Silodosin is for symptomatic treatment of benign prostatic hyperplasia. FDA approved Oct 9, 2008.
Silodosin mechanism of action
Benign prostate hyperplasia (BPH), or an enlarged prostate, is a condition found only in men and is characterized by a non-cancerous enlargement of the prostate gland. Symptoms of BPH include urinary difficulty, urinary frequency and an inability to complete bladder emptying. Silodosin is highly uroselective for the alpha (1A) receptors located in the prostate,[urethrea and bladder trigone in the lower urinary tract]. Blocking these receptors relaxes the smooth muscles, resulting in an improvement in urine flow and a reduction in BPH symptoms. The selective binding of silodosin to the alpha (1A) receptors is substantially greater than the binding to the cardiovascular-associated alpha (1B) receptors and thereby maximizes target organ activity while minimizing the potential for blood pressure effects.[Watson Pharmaceutical Inc. Press release]Silodosin is alpha 1A-adrenoceptor selective antagonist which inhibits sympathetic nerve stimulation and relaxation of smooth muscle tone in the lower urinary tract which relieves the pressure from contraction of smooth muscle. The reduction of intraurethral pressure improves voiding and storage issues associated with BPH.
Dosage forms of Silodosin
KAD 3213 KMD 3213
Physicians Total Care, Inc.
Humans and other mammals
Indication of Silodosin
Treatment for symptomatic relief of benign prostatic hyperplasia
Toxicity of Silodosin
Most common adverse reactions (incidence 2%) are retrograde ejaculation, dizziness, diarrhea, orthostatic hypotension, headache, nasopharyngitis, and nasal congestion.
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What is Rapaflo?
Rapaflo is an alpha adrenergic blocker. Rapaflo helps relax the muscles in the prostate gland and the bladder neck, which makes it easier to urinate. Rapaflo is used to improve urination in men with benign prostatic hyperplasia (an enlarged prostate).
You should not take Rapaflo if you have severe kidney or liver disease. Do not take silodosin with similar drugs such as alfuzosin, doxazosin, prazosin, tamsulosin, or terazosin. Rapaflo may cause dizziness or fainting, especially when you first start taking it. Be careful if you are driving or doing everything that requires your attention. Avoid standing for long periods of time or overheating during exercise and in hot weather. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Rapaflo may affect vac during cataract surgery. Tell your ophthalmologist in advance that you are using Rapaflo. Do not stop using Rapaflo before surgery unless your surgeon asks you. There are many other drugs that can interact with silodosin. Tell your doctor about all medications you use.