Save up -80% on Sirolimus

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
Pharmacists and Patients support.

2019 Price of Sirolimus

Rapamune 0.5 mg tablet

$5.86tablet
price without discount in nearest pharmacy. Price may vary.

Claim your free Sirolimus discount card

We offer free Sirolimus coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Sirolimus every time. What are you waiting for? Claim your prescription drug card now!

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Sirolimus volume of distribution

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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Sirolimus

A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to immunophilins. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.

Sirolimus mechanism of action

Sirolimus inhibits T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (Interleukin IL-2, IL-4, and IL-15) stimulation by a mechanism that is distinct from that of other immunosuppressants. Sirolimus also inhibits antibody production. In cells, sirolimus binds to the immunophilin, FK Binding Protein-12 (FKBP-12), to generate an immunosuppressive complex. The sirolimus:FKBP-12 complex has no effect on calcineurin activity. This complex binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This inhibition suppresses cytokine-driven T-cell proliferation, inhibiting the progression from the G1 to the S phase of the cell cycle.

Dosage forms of Sirolimus

DrugDosageQuantityPrice
Sirolimus1mg90 Tablet$450.00
Rapamune1mg90 Tablet$806.00

Prescription Generics

false

International Brands

Gd-sirolimus

Synonyms

(-)-Rapamycin Rapamycin

Manufacturers

Genmed A Division Of Pfizer Canada Inc

CAS number

53123-88-9

UNII

W36ZG6FT64

State

solid

Affected organisms

Humans and other mammals

Indication of Sirolimus

For the prophylaxis of organ rejection in patients receiving renal transplants.

Toxicity of Sirolimus

RX24 Drugs Disclaimer: before buying a Sirolimus on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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