Save up -80% on Sodium lauryl sulfate
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Sodium lauryl sulfate
Carrington whirlpool solution
|price without discount in nearest pharmacy. Price may vary.|
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Sodium lauryl sulfate volume of distribution
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What is Sodium lauryl sulfate
Sodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. SLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes. It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity.
Sodium lauryl sulfate mechanism of action
Like other surfactants, SLS is amphiphilic. It thus migrates to the surface of liquids, where its alignment and aggregation with other SLS molecules lowers the surface tension. This allows for easier spreading and mixing of the liquid. SLS has potent protein denaturing activity and inhibits the infectivity of viruses by by solubilizing the viral envelope and/or by denaturing envelope and/or capsid proteins.
Dosage forms of Sodium lauryl sulfate
|Paste, dentifrice||oral||.7675 g/100g|
|Paste, dentifrice||oral||1.21 g/160g|
Laurylsiran sodny NaDS
Hanul Trading Co., Ltd.
Humans and other mammals
Indication of Sodium lauryl sulfate
SLS is used as a surfactant in shampoos and toothpastes. SLS also has microbicidal activities against both enveloped (Herpes simplex viruses, HIV-1, Semliki Forest virus) and nonenveloped (papillomaviruses, reovirus, rotavirus and poliovirus) viruses, although it has not been approved for this use.
Toxicity of Sodium lauryl sulfate
Oral (LD50): Acute: 1288 mg/kg (Rat)
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