Save up -80% on Solifenacin

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Solifenacin

Fergon 100 240 (27 Fe)mg tablet Bottle

$15.99

bottle

* price without discount in nearest pharmacy. Price may vary.

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Solifenacin volume of distribution

* 600 L

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What is Solifenacin

Solifenacin (rINN), marketed as solifenacin succinate under the trade name Vesicare, is a urinary antispasmodic of the anticholinergic class. It is used in the treatment of overactive bladder with urge incontinence.[Wikipedia]

Solifenacin mechanism of action

Solifenacin is a competitive muscarinic acetylcholine receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle. By preventing the binding of acetylcholine to these receptors, solifenacin reduces smooth muscle tone in the bladder, allowing the bladder to retain larger volumes of urine and reducing the number of incontinence episodes.

Dosage forms of Solifenacin

DrugDosageQuantityPrice
Solifenacin5mg100 Tablet$28.95
Solifenacin10mg100 Tablet$43.90
Vesicare5mg30 Tablet$59.90
Vesicare5mg90 Tablet$96.70
Vesicare10mg30 Tablet$40.45
Vesicare10mg90 Tablet$101.25
Prescription Generics

false

International Brands

Act Solifenacin

Synonyms

Manufacturers

Actavis Pharma Company

CAS number

242478-37-1

UNII

A8910SQJ1U

State

solid

Affected organisms

Humans and other mammals

Indication of Solifenacin

For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.

Toxicity of Solifenacin

Overdosage with solifenacin can potentially result in severe anticholinergic effects and should be treated accordingly. The highest solifenacin dose given to human volunteers was a single 100 mg dose. Intolerable anticholinergic side effects (fixed and dilated pupils, blurred vision, failure of heel-to-toe exam, tremors and dry skin) occurred on day 3 in normal volunteers taking 50 mg daily (5 times the maximum recommended therapeutic dose).

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